Value Village / Beauty

Do retinol and vitamin C cosmetics really work? What are the precautions?

This answer is a draft. It stays unpublished until legal review and source verification are complete.

The answerRetinol is one of the few ingredients in Japan with an officially recognised claim of "improves wrinkles" (as a quasi-drug, and only in approved products), and the evidence behind it is sound. Vitamin C derivatives are widely used in quasi-drugs with the claim "suppresses melanin production and prevents dark spots and freckles", and they too have supporting evidence. But both have a common problem as cosmetics: irritation in use. Retinol tends to cause redness and peeling (the "retinoid reaction", called "A-hannō" in Japan), and vitamin C tends to sting. The basics are: start at a low concentration two or three times a week, use at night, always wear sunscreen during the day, and avoid retinol during pregnancy. "One bottle and the wrinkles are gone" is expecting too much.

Retinol (a vitamin A derivative) and vitamin C derivatives have become standard ingredients in Japan too, sold for "wrinkle improvement", "pores" and "dullness". In 2017 pure retinol was approved in Japan as a quasi-drug (医薬部外品, a Japanese category between cosmetics and medicines) with the claim "improves wrinkles", and interest took off. If you are used to the rules in your home country, note that what may be claimed here is different. We sort out what is recognised and what is expecting too much.

Where the two ingredients stand

ItemRetinol (vitamin A derivative)Vitamin C derivatives
Approved claim in Japan (quasi-drug)"Improves wrinkles" (approved for pure retinol in 2017; only approved products may state it)"Suppresses melanin production and prevents dark spots and freckles" (ascorbyl glucoside, magnesium ascorbyl phosphate etc.)
Position as a cosmeticUp to "makes fine lines caused by dryness less noticeable" (if an efficacy test has been done)Up to "gives the skin firmness and radiance", "refines skin texture"
Action (shown in research)Speeds up epidermal turnover, promotes collagen production in the dermis, regulates sebumAntioxidant, suppresses melanin production, supports collagen synthesis
IrritationRedness, peeling, dryness (retinoid reaction / A-hannō), most likely in the first 1–4 weeksStinging, dryness (more so in more acidic products)
Light and heatBreaks down in light and oxygen. Use at night, in a light-proof containerOxidises easily (yellow-to-brown discolouration means it has degraded). Derivatives are relatively stable
Combinations to avoidUsing at the same time as peels (AHA/BHA), high-concentration vitamin C or other retinoids stacks up irritationSame. Combining with niacinamide is generally described as fine
Pregnancy and breastfeedingStandard advice is to avoidGenerally described as fine
Time before results show8–12 weeks or more4–12 weeks
[Verify] Check the 2017 retinol approval and the vitamin C derivative claims against the Ministry of Health, Labour and Welfare quasi-drug approval records. Times to results are typical values reported in clinical trials.

Misunderstanding 1|Apply retinol and the wrinkles disappear

The approved claim is "improves wrinkles", which does not mean deep wrinkles disappear. It applies to fine lines at the corners of the eyes, and assumes 12 weeks or more of use.

Misunderstanding 2|Redness or peeling means it does not suit my skin

The retinoid reaction in the first few weeks happens to many people. Reduce the frequency and watch. But stop if there is marked swelling, itching or stinging.

Misunderstanding 3|Vitamin C is acidic, so using it in the morning causes sunburn

Vitamin C derivatives are not phototoxic, and morning use is generally described as fine. Sunscreen is still needed separately.

Misunderstanding 4|Using retinol and a peel together works faster

Stacked irritation breaks down the skin barrier and causes redness and pigmentation instead. Start with one or the other.

Misunderstanding 5|Personally importing a high-strength product from abroad is better value

Tretinoin is a prescription drug, and dermatitis and pigmentation have been reported from self-directed use. Use an approved Japanese product or see a dermatology clinic (covered by Japanese health insurance).

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Sources

https://www.mhlw.go.jp/

https://www.jcss.jp/

https://www.dermatol.or.jp/qa/

⚠️ Editorial note: the source URLs above were identified by search. Our working environment cannot reach go.jp domains, so the contents have not been checked against the text. Verify every source before publication and record who checked it and when.

About this article

What we share here are ideas and everyday practices passed down among people living in Japan, together with general information drawn from public sources. They are not official recommendations, and they are not professional instruction. Practices vary between households and regions.

This is general information. Results vary from person to person and depend on your own conditions and surroundings.

Please decide for yourself, using your own judgement, whether any of this suits your situation. We cannot accept responsibility for any damage, loss or injury arising from following this article.

Cosmetics are not medicines and are not meant to diagnose, heal or prevent any condition. If your skin reacts, stop using the product and see a dermatologist.

Sources

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