Hakua Series (Advance)

Highly formulated with human umbilical cord blood cell conditioned culture medium, a moisturizing ingredient also attracting attention in the field of regenerative medicine.

Human umbilical cord blood cell conditioned culture medium is the supernatant obtained when stem cells derived from a newborn baby's umbilical cord, collected at the time of birth, are cultured, and it contains abundant bioactive substances such as cytokines, growth factors, and amino acids.

As a moisturizing and skin-conditioning ingredient, human umbilical cord blood cell conditioned culture medium helps protect moisture in mature skin and leads to the appearance of smooth, refined skin. It penetrates thoroughly to the stratum corneum and helps balance skin moisture, addressing concerns such as dullness caused by dryness and lack of firmness.

Related to the skin's moisture retention and barrier function Niacinamide, it is formulated with a vitamin C derivative, bis-glyceryl ascorbic acid, that easily penetrates to the stratum corneum, taking a multifaceted approach to dullness caused by dryness and uneven texture.

It also contains highly moisturizing sodium hydrolyzed hyaluronate and sodium hyaluronate, trehalose, glycerin to support the skin's moisture balance.
In addition, placenta extract, dipotassium glycyrrhizate, allantoin and other skin-conditioning ingredients help prevent skin roughness caused by external stresses such as dryness, leading to a healthy skin environment.

Naturally derived citrus fruit extracts, orange, lemon, lime, grapefruit and apple fruit extract, jujube fruit extract and others are also included, offering a gentle feel on the skin and the pleasant aroma of natural ingredients as part of its appeal.

This product uses ingredients from INVITRX of the United States, a company highly regarded in the field of regenerative medicine. Using ingredients manufactured in GMP-compliant, FDA-registered facilities under sanitary management, it is carefully formulated and finished in Japan.